DOSSIER · 13F Holders · Q4 2025Healthcare · Pharmaceutical PreparationsDefensive growthQuality
GOSS

GOSSAMER BIO INC

201 institutions still hold GOSSAMER BIO INC as of Q4 2025. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 38341P102·Pharmaceutical Preparations·201 13F holders·last filed Dec 31, 2025
Market cap
8.6%
vs prior quarter
13F value held
$81M
73.0% inst. owned
of float
Holders
201
+111 QoQ
filers reporting
Activity
+16 / −90
+892 added · −701 reduced
this quarter
Concentration
21.01%
683 Capital Management, LLC #1
top holder share
AI Holders Summary · Q4 2025

201 institutions reported GOSS in Q4 2025. 683 Capital Management, LLC leads at 21.0% of the visible book. +111 net new institutions vs prior quarter — accumulation reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
683 Capital Management, LLC
CIK 0001404574
$17M5.5M0.74%Q4 2025
02
Opaleye Management Inc.
CIK 0001595855
$8M2.7M1.11%Q4 2025
03
TWO SIGMA ADVISERS, LP
CIK 0001478735
$8M2.6M0.02%Q4 2025
04
Kalehua Capital Management LLC
CIK 0002106181
$6M17.7M2.24%Q1 2026
05
BlackRock, Inc.
CIK 0002012383
$6M16.8M0.00%Q1 2026
06
CITADEL ADVISORS LLC
CIK 0001423053
$5M1.6M0.00%Q4 2025
07
AQR CAPITAL MANAGEMENT LLC
CIK 0001167557
$3M10.1M0.00%Q1 2026
08
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$3M9.4M0.00%Q1 2026
09
HRT FINANCIAL LP
CIK 0001475597
$3M957K0.01%Q4 2025
10
Alyeska Investment Group, L.P.
CIK 0001453072
$3M909K0.01%Q4 2025
11
ARCH Venture Management, LLC
CIK 0001274403
$3M8.1M0.39%Q1 2026
12
Octagon Capital Advisors LP
CIK 0001839435
$3M7.8M0.28%Q1 2026
13
Samsara BioCapital, LLC
CIK 0001744967
$2M7.2M0.23%Q1 2026
14
BALYASNY ASSET MANAGEMENT L.P.
CIK 0001218710
$2M5.9M0.00%Q1 2026
15
Siren, L.L.C.
CIK 0002005245
$2M5.2M0.05%Q1 2026
16
HHLR ADVISORS, LTD.
CIK 0001762304
$2M5.0M0.10%Q1 2026
17
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$2M4.9M0.00%Q1 2026
18
Qube Research & Technologies Ltd
CIK 0001729829
$2M4.9M0.00%Q1 2026
19
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
$2M4.8M0.00%Q1 2026
20
STATE STREET CORP
CIK 0000093751
$1M4.4M0.00%Q1 2026
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