AI Holders Summary · Q4 2025

200 institutions reported GOSS in Q4 2025. 683 Capital Management, LLC leads at 21.1% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(2 on this page)

#HolderValueShares% port.Quarter

683 Capital Management, LLC

CIK 0001404574

$17M5.5M0.74%Q4 2025 02

Opaleye Management Inc.

CIK 0001595855

$8M2.7M1.11%Q4 2025 03

TWO SIGMA ADVISERS, LP

CIK 0001478735

$8M2.6M0.02%Q4 2025 04

Kalehua Capital Management LLC

CIK 0002106181

$6M17.7M2.24%Q1 2026 05

CITADEL ADVISORS LLC

CIK 0001423053

$5M1.6M0.00%Q4 2025 06

Context Capital Management, LLC

CIK 0001301396

$5M28.9M0.09%Q2 2026 07

AQR CAPITAL MANAGEMENT LLC

CIK 0001167557

$3M10.1M0.00%Q1 2026 08

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$3M9.4M0.00%Q1 2026 09

HRT FINANCIAL LP

CIK 0001475597

$3M957K0.01%Q4 2025 10

Alyeska Investment Group, L.P.

CIK 0001453072

$3M909K0.01%Q4 2025 11

ARCH Venture Management, LLC

CIK 0001274403

$3M8.1M0.39%Q1 2026 12

Octagon Capital Advisors LP

CIK 0001839435

$3M7.8M0.28%Q1 2026 13

Samsara BioCapital, LLC

CIK 0001744967

$2M7.2M0.23%Q1 2026 14

BALYASNY ASSET MANAGEMENT L.P.

CIK 0001218710

$2M5.9M0.00%Q1 2026 15

ACADIAN ASSET MANAGEMENT LLC

CIK 0000916542

$2M5.3M0.00%Q1 2026 16

Siren, L.L.C.

CIK 0002005245

$2M5.2M0.05%Q1 2026 17

HHLR ADVISORS, LTD.

CIK 0001762304

$2M5.0M0.10%Q1 2026 18

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$2M4.9M0.00%Q1 2026 19

Qube Research & Technologies Ltd

CIK 0001729829

$2M4.9M0.00%Q1 2026 20

TWO SIGMA INVESTMENTS, LP

CIK 0001179392

$2M4.8M0.00%Q1 2026

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