AI Holders Summary · Q2 2026

88 institutions reported PBLS in Q2 2026. RA CAPITAL MANAGEMENT, L.P. leads at 35.3% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(3 on this page)

#HolderValueShares% port.Quarter

RA CAPITAL MANAGEMENT, L.P.

CIK 0001346824

$792M28.9M6.88%Q2 2026 02

FMR LLC

CIK 0000315066

$282M10.3M0.01%Q2 2026 03

ARCH Venture Management, LLC

CIK 0001274403

$176M6.4M15.95%Q2 2026 04

Alphabet Inc.

CIK 0001652044

$159M4.9M0.18%Q3 2026 05

REGENERON PHARMACEUTICALS, INC.

CIK 0000872589

$135M4.2M74.90%Q3 2026 06

Cormorant Asset Management, LP

CIK 0001583977

$126M4.6M6.47%Q2 2026 07

Siren, L.L.C.

CIK 0002005245

$82M3.0M1.66%Q2 2026 08

FARALLON CAPITAL MANAGEMENT LLC

CIK 0000909661

$65M2.4M0.30%Q2 2026 09

Jupiter Topco LLC

CIK 0002146052

$63M2.3M0.03%Q2 2026 10

Frazier Life Sciences Management, L.P.

CIK 0001892134

$53M1.9M1.14%Q2 2026 11

General Catalyst Group Management, LLC

CIK 0001637946

$44M1.6M23.24%Q2 2026 12

GENERAL ATLANTIC, L.P.

CIK 0001017645

$42M1.5M1.45%Q2 2026 13

Soleus Capital Management, L.P.

CIK 0001802630

$40M1.5M1.38%Q2 2026 14

Vanguard Portfolio Management

CIK 0002100121· Index

$36M1.3M0.00%Q2 2026 15

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$32M1.0M0.00%Q3 2026 16

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$32M1.2M0.00%Q2 2026 17

JPMORGAN CHASE & CO

CIK 0000019617

$30M1.0M0.00%Q2 2026 18

Catalio Capital Management, LP

CIK 0001958125

$23M824K4.24%Q2 2026 19

Casdin Capital, LLC

CIK 0001534261

$18M646K0.88%Q2 2026 20

Rock Springs Capital Management LP

CIK 0001595725

$16M578K0.77%Q2 2026

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