13F Insight
DOSSIER · 13F Holders · Q1 2026Inflation hedgeYield
PRLD

PRELUDE THERAPEUTICS INC

55 institutions still hold PRELUDE THERAPEUTICS INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 74065P101·55 13F holders·last filed Mar 31, 2026
Market cap
—
▲ 9.7%
vs prior quarter
13F value held
$96M
60.0% inst. owned
of float
Holders
55
+126 QoQ
filers reporting
Activity
+82 / −6
+1,040 added · −923 reduced
this quarter
Concentration
39.03%
ORBIMED ADVISORS LLC #1
top holder share
AI Holders Summary · Q1 2026

55 institutions reported PRLD in Q1 2026. ORBIMED ADVISORS LLC leads at 39.0% of the visible book. +126 net new institutions vs prior quarter — accumulation reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
ORBIMED ADVISORS LLC
CIK 0001055951
$37M10.9M0.74%Q1 202602
BAKER BROS. ADVISORS LP
CIK 0001263508
$29M10.1M0.17%Q4 202503
Kynam Capital Management, LP
CIK 0001907884
$5M1.6M0.34%Q1 202604
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$4M1.2M0.00%Q1 202605
EcoR1 Capital, LLC
CIK 0001587114
$3M947K0.14%Q1 202606
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
$3M924K0.00%Q1 202607
SPHERA FUNDS MANAGEMENT LTD.
CIK 0001496201
$2M558K0.30%Q1 202608
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
$1M383K0.00%Q1 202609
MORGAN STANLEY
CIK 0000895421
$1M322K0.00%Q1 202610
BlackRock, Inc.
CIK 0002012383
$1M322K0.00%Q1 202611
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$1M302K0.00%Q1 202612
SUSQUEHANNA INTERNATIONAL GROUP, LLP
CIK 0001446194· Market maker
$987,655289K0.00%Q1 202613
RENAISSANCE TECHNOLOGIES LLC
CIK 0001037389
$941,184275K0.00%Q1 202614
GOLDMAN SACHS GROUP INC
CIK 0000886982
$808,724236K0.00%Q1 202615
MARSHALL WACE, LLP
CIK 0001318757
$794,260274K0.00%Q4 202516
TWO SIGMA ADVISERS, LP
CIK 0001478735
$688,170237K0.00%Q4 202517
JANE STREET GROUP, LLC
CIK 0001595888· Market maker
$659,933193K0.00%Q1 202618
VANGUARD FIDUCIARY TRUST CO
CIK 0000933478· Index
$538,240157K0.00%Q1 202619
ADAR1 Capital Management, LLC
CIK 0001940272
$522,662153K0.03%Q1 202620
STATE STREET CORP
CIK 0000093751
$472,750138K0.00%Q1 2026
Page 1 of 3
35 more holders available. Log in →