AI Holders Summary · Q1 2026

106 institutions reported RLMD in Q1 2026. JANUS HENDERSON GROUP PLC leads at 18.8% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(3 on this page)

#HolderValueShares% port.Quarter

JANUS HENDERSON GROUP PLC

CIK 0001274173

$77M11.1M0.04%Q1 2026 02

Spruce Street Capital LP

CIK 0002050194

$43M6.3M10.34%Q1 2026 03

ADAGE CAPITAL PARTNERS GP, L.L.C.

CIK 0001165408

$33M4.8M0.05%Q1 2026 04

ORBIMED ADVISORS LLC

CIK 0001055951

$33M4.7M0.65%Q1 2026 05

Squadron Capital Management LLC

CIK 0002050709

$32M6.7M13.71%Q4 2025 06

MILLENNIUM MANAGEMENT LLC

CIK 0001273087

$27M3.9M0.01%Q1 2026 07

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$21M3.1M0.00%Q1 2026 08

RA CAPITAL MANAGEMENT, L.P.

CIK 0001346824

$21M2.9M0.22%Q1 2026 09

Ikarian Capital, LLC

CIK 0001778253

$19M2.7M1.52%Q1 2026 10

MARSHALL WACE, LLP

CIK 0001318757

$15M3.2M0.01%Q4 2025 11

DRIEHAUS CAPITAL MANAGEMENT LLC

CIK 0000938206

$15M2.1M0.11%Q1 2026 12

AMERIPRISE FINANCIAL INC

CIK 0000820027

$11M1.6M0.00%Q1 2026 13

Polar Capital Holdings Plc

CIK 0001837309

$10M1.4M0.04%Q1 2026 14

SUSQUEHANNA INTERNATIONAL GROUP, LLP

CIK 0001446194· Market maker

$9M1.3M0.00%Q1 2026 15

BlackRock, Inc.

CIK 0002012383

$9M1.3M0.00%Q1 2026 16

STEMPOINT CAPITAL LP

CIK 0001952142

$8M1.2M0.80%Q1 2026 17

Sio Capital Management, LLC

CIK 0001482416

$7M965K0.96%Q1 2026 18

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$6M849K0.00%Q1 2026 19

EVENTIDE ASSET MANAGEMENT, LLC

CIK 0001442891

$6M842K0.10%Q1 2026 20

Boxer Capital Management, LLC

CIK 0002018299

$6M842K0.77%Q1 2026

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