13F Insight
DOSSIER · 13F Holders · Q1 2026BellwetherCompounder
TSHA

TAYSHA GENE THERAPIES INC

203 institutions still hold TAYSHA GENE THERAPIES INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 877619106·203 13F holders·last filed Mar 31, 2026
Market cap
—
▼ 5.3%
vs prior quarter
13F value held
$1.0B
66.0% inst. owned
of float
Holders
203
-92 QoQ
filers reporting
Activity
+20 / −31
+896 added · −788 reduced
this quarter
Concentration
10.47%
RA CAPITAL MANAGEMENT, L.P. #1
top holder share
AI Holders Summary · Q1 2026

203 institutions reported TSHA in Q1 2026. RA CAPITAL MANAGEMENT, L.P. leads at 10.5% of the visible book. -92 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
RA CAPITAL MANAGEMENT, L.P.
CIK 0001346824
$105M23.6M1.12%Q1 202602
GOLDMAN SACHS GROUP INC
CIK 0000886982
$100M22.4M0.01%Q1 202603
Avoro Capital Advisors LLC
CIK 0001633313
$97M21.7M0.95%Q1 202604
BlackRock, Inc.
CIK 0002012383
$82M18.4M0.00%Q1 202605
Vestal Point Capital, LP
CIK 0001974915
$80M18.0M2.25%Q1 202606
MORGAN STANLEY
CIK 0000895421
$80M18.0M0.00%Q1 202607
FMR LLC
CIK 0000315066
$64M14.3M0.00%Q1 202608
RTW INVESTMENTS, LP
CIK 0001493215
$61M13.7M0.61%Q1 202609
STATE STREET CORP
CIK 0000093751
$50M11.2M0.00%Q1 202610
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$46M10.2M0.00%Q1 202611
Octagon Capital Advisors LP
CIK 0001839435
$40M8.9M4.38%Q1 202612
Siren, L.L.C.
CIK 0002005245
$39M8.8M1.09%Q1 202613
Polar Capital Holdings Plc
CIK 0001837309
$25M5.7M0.09%Q1 202614
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$25M5.5M0.00%Q1 202615
GordonMD Global Investments LP
CIK 0002039349
$22M738K15.47%Q1 202616
D. E. Shaw & Co., Inc.
CIK 0001009207
$22M4.0M0.01%Q4 202517
BAKER BROS. ADVISORS LP
CIK 0001263508
$22M4.0M0.13%Q4 202518
DEERFIELD MANAGEMENT COMPANY, L.P.
CIK 0001009258
$15M2.7M0.19%Q4 202519
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
$15M3.3M0.01%Q1 202620
Casdin Capital, LLC
CIK 0001534261
$15M3.3M1.10%Q1 2026
Page 1 of 11
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