DOSSIER · 13F Holders · Q1 2026CyclicalNet sold
AMLX

AMYLYX PHARMACEUTICALS INC

179 institutions still hold AMYLYX PHARMACEUTICALS INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 03237H101·179 13F holders·last filed Mar 31, 2026
Market cap
4.8%
vs prior quarter
13F value held
$1.2B
75.0% inst. owned
of float
Holders
179
-85 QoQ
filers reporting
Activity
+66 / −56
+796 added · −787 reduced
this quarter
Concentration
19.06%
FMR LLC #1
top holder share
AI Holders Summary · Q1 2026

179 institutions reported AMLX in Q1 2026. FMR LLC leads at 19.1% of the visible book. -85 net institutions QoQ — distribution reading.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
FMR LLC
CIK 0000315066
$231M16.6M0.01%Q1 2026
02
BlackRock, Inc.
CIK 0002012383
$123M8.8M0.00%Q1 2026
03
PERCEPTIVE ADVISORS LLC
CIK 0001224962
$115M8.3M2.25%Q1 2026
04
TCG Crossover Management, LLC
CIK 0001839948
$87M6.2M2.48%Q1 2026
05
Commodore Capital LP
CIK 0001831942
$79M5.7M4.54%Q1 2026
06
JANUS HENDERSON GROUP PLC
CIK 0001274173
$69M5.0M0.03%Q1 2026
07
Saturn V Capital Management LP
CIK 0001964437
$60M4.3M10.95%Q1 2026
08
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$58M4.1M0.00%Q1 2026
09
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
$49M3.6M0.08%Q1 2026
10
First Light Asset Management, LLC
CIK 0001600004
$44M3.2M3.97%Q1 2026
11
DRIEHAUS CAPITAL MANAGEMENT LLC
CIK 0000938206
$42M3.0M0.31%Q1 2026
12
GOLDMAN SACHS GROUP INC
CIK 0000886982
$37M2.6M0.00%Q1 2026
13
STATE STREET CORP
CIK 0000093751
$33M2.4M0.00%Q1 2026
14
FRANKLIN RESOURCES INC
CIK 0000038777
$31M2.3M0.01%Q1 2026
15
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$31M2.2M0.00%Q1 2026
16
MORGAN STANLEY
CIK 0000895421
$30M2.2M0.00%Q1 2026
17
Almitas Capital LLC
CIK 0001596468
$30M2.1M6.67%Q1 2026
18
Jones Hill Capital LP
CIK 0002102314
$22M1.6M4.76%Q1 2026
19
GREAT POINT PARTNERS LLC
CIK 0001281446
$21M1.8M6.85%Q4 2025
20
EVENTIDE ASSET MANAGEMENT, LLC
CIK 0001442891
$21M1.5M0.35%Q1 2026
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