AI Holders Summary · Q2 2026

199 institutions reported GPCR in Q2 2026. FMR LLC leads at 12.7% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter

FMR LLC

CIK 0000315066

$419M7.8M0.02%Q2 2026 02

WELLINGTON MANAGEMENT GROUP LLP

CIK 0000902219

$396M7.4M0.07%Q2 2026 03

Avoro Capital Advisors LLC

CIK 0001633313

$352M6.6M3.16%Q2 2026 04

Jupiter Topco LLC

CIK 0002146052

$279M5.2M0.11%Q2 2026 05

JANUS HENDERSON GROUP PLC

CIK 0001274173

$258M5.4M0.12%Q1 2026 06

Deep Track Capital, LP

CIK 0001856083

$254M4.7M3.70%Q2 2026 07

BVF INC/IL

CIK 0001056807

$242M3.5M8.15%Q4 2025 08

MORGAN STANLEY

CIK 0000895421

$151M2.8M0.01%Q2 2026 09

ORBIMED ADVISORS LLC

CIK 0001055951

$119M2.2M2.21%Q2 2026 10

BAKER BROS. ADVISORS LP

CIK 0001263508

$100M1.4M0.58%Q4 2025 11

PRICE T ROWE ASSOCIATES INC /MD/

CIK 0000080255

$96M2.0M0.01%Q1 2026 12

PRINCIPAL FINANCIAL GROUP INC

CIK 0001126328

$94M1.8M0.05%Q2 2026 13

AMERICAN CENTURY COMPANIES INC

CIK 0000748054

$90M1.7M0.04%Q2 2026 14

RTW INVESTMENTS, LP

CIK 0001493215

$86M1.6M0.74%Q2 2026 15

DRIEHAUS CAPITAL MANAGEMENT LLC

CIK 0000938206

$83M1.6M0.48%Q2 2026 16

Casdin Capital, LLC

CIK 0001534261

$63M1.2M3.16%Q2 2026 17

Capitolis Liquid Global Markets LLC

CIK 0001960050

$61M878K0.36%Q4 2025 18

CAPITOLIS LIQUID GLOBAL MARKETS LLC

CIK 0002094379

$56M1.0M0.24%Q2 2026 19

DEERFIELD MANAGEMENT COMPANY, L.P.

CIK 0001009258

$53M768K0.68%Q4 2025 20

Siren, L.L.C.

CIK 0002005245

$47M873K0.95%Q2 2026

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