AI Holders Summary · Q1 2026

197 institutions reported GPCR in Q1 2026. FMR LLC leads at 14.6% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter

FMR LLC

CIK 0000315066

$405M8.4M0.02%Q1 2026 02

WELLINGTON MANAGEMENT GROUP LLP

CIK 0000902219

$350M7.3M0.07%Q1 2026 03

Avoro Capital Advisors LLC

CIK 0001633313

$316M6.6M3.11%Q1 2026 04

JANUS HENDERSON GROUP PLC

CIK 0001274173

$258M5.4M0.12%Q1 2026 05

BVF INC/IL

CIK 0001056807

$242M3.5M8.15%Q4 2025 06

Deep Track Capital, LP

CIK 0001856083

$206M4.3M3.37%Q1 2026 07

MORGAN STANLEY

CIK 0000895421

$111M2.3M0.01%Q1 2026 08

BAKER BROS. ADVISORS LP

CIK 0001263508

$100M1.4M0.58%Q4 2025 09

PRICE T ROWE ASSOCIATES INC /MD/

CIK 0000080255

$96M2.0M0.01%Q1 2026 10

PRINCIPAL FINANCIAL GROUP INC

CIK 0001126328

$85M1.8M0.05%Q1 2026 11

DRIEHAUS CAPITAL MANAGEMENT LLC

CIK 0000938206

$76M1.6M0.56%Q1 2026 12

ORBIMED ADVISORS LLC

CIK 0001055951

$71M1.5M1.42%Q1 2026 13

AMERICAN CENTURY COMPANIES INC

CIK 0000748054

$69M1.4M0.04%Q1 2026 14

Siren, L.L.C.

CIK 0002005245

$64M1.3M1.78%Q1 2026 15

CITADEL ADVISORS LLC

CIK 0001423053

$63M907K0.01%Q4 2025 16

Capitolis Liquid Global Markets LLC

CIK 0001960050

$61M878K0.36%Q4 2025 17

Casdin Capital, LLC

CIK 0001534261

$57M1.2M4.29%Q1 2026 18

CAPITOLIS LIQUID GLOBAL MARKETS LLC

CIK 0002094379

$55M1.2M0.35%Q1 2026 19

DEERFIELD MANAGEMENT COMPANY, L.P.

CIK 0001009258

$53M768K0.68%Q4 2025 20

ALLIANCEBERNSTEIN L.P.

CIK 0001109448

$44M639K0.01%Q1 2026

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