DOSSIER · 13F Holders · Q1 2026
TECX

TECTONIC THERAPEUTIC INC

118 institutions still hold TECTONIC THERAPEUTIC INC as of Q1 2026. Tracked across SEC 13F-HR filings, with insider and 13D/G activity surfaced alongside.

CUSIP 878972108·118 13F holders·last filed Mar 31, 2026
Market cap
13F value held
$361M
visible holders
Holders
118
filers reporting
Concentration
24.12%
FMR LLC #1
top holder share
AI Holders Summary · Q1 2026

Tectonic Therapeutics Inc. (TECX, CUSIP 878972108) entered Q1 2026 with $400M of institutional 13F value across 105 institutional accounts — an appropriately concentrated holder profile for a pre-clinical-stage biotechnology company focused on regenerative medicine and tissue-engineering platforms, whose investor base consists of early-stage BIOPHARMA conviction and special-situations managers rather than diversified large-cap strategies. The defining Q1 signals: eight new positions opened in a 105-holder universe (a 7.6% holder-base expansion in a single quarter), FMR LLC added $28M, and Point72 Asset Management reduced only $8M — a near-net-positive rotation at the biotech-conviction tier that is consistent with fundamental-manager conviction building in regenerative-medicine / tissue-engineering ahead of a clinical-readout catalyst. For smart-money trackers, TECX is at the earliest institutional-coverage inflection point: the 8-new-position event in a compact holder universe is a stronger IQ signal than any dollar-size rotation, because it represents coordinated early-stage-coverage expansion by biotech specialists rather than late-stage positioning by large generalist managers.

Q1 2026 context: regenerative medicine and tissue engineering has attracted significant institutional interest as the field matures from concept toward clinical validation. Key questions: (1) platform-protection IP position, (2) pre-clinical data quality and translatability to human indications, (3) potential big-pharma partnership interest (typical exit/development path for platform biotechs at this stage), (4) cash runway and capital structure.

8 new positions in 105-holder universe = early-stage-coverage expansion. FMR +$28M is the dominant buy: FMR is building at the conviction tier for a platform biotech, indicating strong fundamental belief.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

#HolderValueShares% port.Quarter
01
FMR LLC
CIK 0000315066
$87M2.8M0.00%Q1 2026
02
TCG Crossover Management, LLC
CIK 0001839948
$37M1.2M1.07%Q1 2026
03
Aberdeen Group plc
CIK 0001716774
$35M1.1M0.06%Q1 2026
04
BlackRock, Inc.
CIK 0002012383
$27M860K0.00%Q1 2026
05
BRAIDWELL LP
CIK 0001920938
$26M847K0.87%Q1 2026
06
First Light Asset Management, LLC
CIK 0001600004
$20M648K1.79%Q1 2026
07
BAKER BROS. ADVISORS LP
CIK 0001263508
$19M903K0.11%Q4 2025
08
VANGUARD CAPITAL MANAGEMENT LLC
CIK 0002100119· Index
$15M474K0.00%Q1 2026
09
5AM Venture Management, LLC
CIK 0001799883
$13M607K3.98%Q4 2025
10
Vestal Point Capital, LP
CIK 0001974915
$10M328K0.28%Q1 2026
11
Bollard Group LLC
CIK 0001556218
$9M303K0.28%Q1 2026
12
SUSQUEHANNA INTERNATIONAL GROUP, LLP
CIK 0001446194· Market maker
$9M293K0.00%Q1 2026
13
KENNEDY CAPITAL MANAGEMENT LLC
CIK 0000884589
$9M287K0.19%Q1 2026
14
GEODE CAPITAL MANAGEMENT, LLC
CIK 0001214717· Index
$8M268K0.00%Q1 2026
15
CITADEL ADVISORS LLC
CIK 0001423053
$8M385K0.00%Q4 2025
16
ORBIMED ADVISORS LLC
CIK 0001055951
$7M227K0.14%Q1 2026
17
STATE STREET CORP
CIK 0000093751
$7M214K0.00%Q1 2026
18
Squarepoint Ops LLC
CIK 0001642575
$5M164K0.01%Q1 2026
19
PRICE T ROWE ASSOCIATES INC /MD/
CIK 0000080255
$5M164K0.00%Q1 2026
20
Ikarian Capital, LLC
CIK 0001778253
$5M158K0.40%Q1 2026
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Insiders at TECTONIC THERAPEUTIC INC
Mcnamara PeterReicin AliseDonenberg Phillip B.Tipirneni Praveen P.Vitorovic StefanSpringer Timothy AChutter Jessica CarolineNader Francois