AI Holders Summary · Q1 2026

56 institutions reported QTTB in Q1 2026. ORBIMED ADVISORS LLC leads at 28.0% of the visible book.

Top holders

Sorted by position value. Source: SEC EDGAR 13F-HR filings.

Hide index funds / market makers / custodians(4 on this page)

#HolderValueShares% port.Quarter

ORBIMED ADVISORS LLC

CIK 0001055951

$14M2.3M0.29%Q1 2026 02

Atlas Venture Life Science Advisors, LLC

CIK 0001917529

$13M2.1M1.70%Q1 2026 03

Carlyle Group Inc.

CIK 0001527166

$7M1.1M0.07%Q1 2026 04

ARCH Venture Management, LLC

CIK 0001274403

$2M320K0.30%Q1 2026 05

ACORN CAPITAL ADVISORS, LLC

CIK 0002054410

$2M315K0.57%Q1 2026 06

VANGUARD CAPITAL MANAGEMENT LLC

CIK 0002100119· Index

$2M306K0.00%Q1 2026 07

MACKENZIE FINANCIAL CORP

CIK 0000919859

$2M246K0.00%Q1 2026 08

Sanofi

CIK 0001121404

$2M244K0.47%Q1 2026 09

RENAISSANCE TECHNOLOGIES LLC

CIK 0001037389

$1M207K0.00%Q1 2026 10

ACADIAN ASSET MANAGEMENT LLC

CIK 0000916542

$1M173K0.00%Q1 2026 11

MONIMUS CAPITAL MANAGEMENT, LP

CIK 0001848831

$862K134K0.24%Q1 2026 12

GEODE CAPITAL MANAGEMENT, LLC

CIK 0001214717· Index

$759K118K0.00%Q1 2026 13

PFIZER INC

CIK 0000078003

$737K102K0.31%Q1 2026 14

Opaleye Management Inc.

CIK 0001595855

$708K213K0.09%Q4 2025 15

BlackRock, Inc.

CIK 0002012383

$553K86K0.00%Q1 2026 16

JANE STREET GROUP, LLC

CIK 0001595888· Market maker

$421K66K0.00%Q1 2026 17

VANGUARD FIDUCIARY TRUST CO

CIK 0000933478· Index

$321K50K0.00%Q1 2026 18

TWO SIGMA INVESTMENTS, LP

CIK 0001179392

$272K42K0.00%Q1 2026 19

STATE STREET CORP

CIK 0000093751

$267K42K0.00%Q1 2026 20

Cambridge Investment Research Advisors, Inc.

CIK 0001419186

$225K35K0.00%Q1 2026

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